(XLS 55 KB) Additional file 2: Complete list of all classes identified. This is an Excel file listing all classes identified in each pig tonsil sample and the number of unique sequences belonging to each class within each sample, in descending

order of frequency found in the total data set. Horizontal divisions indicate classes found in all samples, those found in Herd 2 only, and those found in Herd 1 only. Classes that comprise the core microbiome are highlighted. (XLS 58 KB) Additional file 3: Complete list of all orders identified. This is an Excel file listing all orders identified in each pig tonsil sample and the number of unique sequences belonging Temsirolimus to each order within each sample, in descending order of frequency found in the total data set. Horizontal divisions indicate orders found in all samples, those found in Herd 2 only, and those found in Herd 1 only. Orders that comprise the core microbiome are highlighted. (XLS 48 KB) Additional file 4: Complete list of all families identified. This is an Excel file listing

all families identified in each pig tonsil sample and the number of Nutlin-3a research buy unique sequences belonging to each family within each sample, in descending order of frequency found in the total data set. Horizontal divisions indicate families found in all samples, those found in Herd 2 only, and those found in Herd 1 only. Families that comprise the core microbiome are highlighted. (XLS 76 KB) Additional file 5: Complete list of all genera identified. This is an Excel file listing all genera identified in each pig tonsil sample and the number of unique sequences belonging STK38 to each genus within each sample, in descending order of frequency found in the total data set. Horizontal divisions indicate genera found in all samples, those found in Herd 2 only, and those found in Herd 1 only. Genera that comprise the core microbiome are highlighted. (XLS 90 KB) References

1. buy PF-02341066 Horter DC, Yoon KJ, Zimmerman JJ: A review of porcine tonsils in immunity and disease. Anim Health Res Rev 2003,4(2):143–155.PubMedCrossRef 2. Belz GT, Heath TJ: Tonsils of the soft palate of young pigs: crypt structure and lymphoepithelium. Anat Rec 1996,245(1):102–113.PubMedCrossRef 3. Arends JP, Hartwig N, Rudolphy M, Zanen HC: Carrier rate of Streptococcus sui capsular type 2 in palatine tonsils of slaughtered pigs. J Clin Microbiol 1984,20(5):945–947.PubMed 4. Chiers K, Donne E, Van Overbeke I, Ducatelle R, Haesebrouck F: Actinobacillus pleuropneumonia infections in closed swine herds: infection patterns and serological profiles. Vet Microbiol 2002,85(4):343–352.PubMedCrossRef 5. Horter DC, Pogranichniy RM, Chang CC, Evans RB, Yoon KJ, Zimmerman JJ: Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infection. Vet Microbiol 2002,86(3):213–228.PubMedCrossRef 6. Cheville NF, Mengeling WL: The pathogenesis of chronic hog cholera (swine fever).