We presented masks and primes simultaneously in short stimulus onset asynchrony (SOA) conditions, and introduced a blank screen between mask and target in long SOA conditions (see e.g., Boy et al., 2010a; 2010b; Boy and Sumner, 2010; Schlaghecken et al., 2006, 2003; Schlaghecken and Eimer, 2002; Schlaghecken and Maylor, 2005). It is possible that differences in the short- and long-SOA trial sequence may affect global RTs – for example the offset of the mask in the long SOA condition may serve as a warning

signal that the target is about to appear and thus speed responses selleck kinase inhibitor in the long SOA condition. However, as such effects are expected to have a global influence on RTs, and not affect one condition (compatible or incompatible) or hand (alien or non-alien) more than the other, they should

not be able to account for any differences in compatibility effect shown in the different hands. Each trial began with presentation of a white fixation cross on a mid-grey background. This cross subtended 1 degree × 1 degree of visual angle, and was presented in the centre of the screen for 500 msec. Following a blank interval of 200 msec, the prime appeared in the centre of the screen and remained for 50 msec (see below for how this duration was determined). The prime was then replaced with the mask which remained on the screen for 100 msec. Buparlisib concentration Two mask-target SOAs were used in this experiment; 20 msec (short SOA, which was expected to produce a PCE) and 150 msec (long SOA, which was expected to produce an NCE). SOA conditions were presented in alternating blocks, starting cAMP with a long SOA block. Patient SA completed 8 blocks (4 of each SOA condition) of 84 trials

each, making a total of 672 trials. A schematic of the stimuli and timings for this task can be seen in Fig. 4. Note that the total presentation time of each stimulus (prime, mask, target) was the same in both SOA conditions. The target stimulus appeared after the mask had onset, and was either a left-, or right-pointing double arrowhead (so that it was either compatible or incompatible with the prime stimulus). The target appeared in one of three possible locations, centred 5 degrees of visual angle to the left, to the right, or above the centre of the screen. The participant was instructed to ignore the target’s position, and to respond to the direction of this arrowhead by squeezing with either the left hand (for left-pointing targets) or the right hand (for right-pointing targets) as quickly and accurately as possible. In each block of trials there were an equal number of trials with each target type (left-, and right-pointing) in each possible position (left-, right-, above-centre), with each prime type (compatible and incompatible), presented in randomly shuffled order determined independently for each block. The target stimulus remained on the screen for 200 msec.