There is less familial Ixazomib aggregation, lower incidence of CRC in IBD, and less NOD2/CARD15 gene mutation in Chinese population compared to the Western population. Further studies to identify unique genetic susceptibilities and environmental influences in Chinese population are needed.The collection of accurate epidemiologic data in China has been hampered by the lack of nationwide IBD registry. Most retrospective hospital-derived data may lead to an underestimate of the incidence rate and an overestimate of disease severity. It is difficult to know whether the current epidemiology data mainly from single province and for short period can represent the whole Chinese population because different parts of China are undergoing different rates of industrialization and westernization.
The nationwide population-based epidemiologic study over a long period is called urgently.
Biological combustion involved in various processes produces harmful products or intermediates called reactive oxygen species or free radicals. Excess of free radicals in living beings has been known to cause various problems like asthma, cancer, cardiovascular diseases, liver diseases, muscular degeneration, and other inflammatory processes [1], resulting in the so-called oxidative stress. Oxidative stress is defined as imbalance between oxidants and antioxidants and causes damage in all types of biomolecules like protein, nucleic acid, DNA, and RNA [2]. Hence, the balance between reactive species or free radicals and antioxidants is believed to be a critical concept for maintaining a good biological system.
Antioxidants act as free radical scavengers, reducing agents, quenchers of singlet oxygen molecule, and activators for antioxidative enzyme to suppress the damage induced by free radicals in biological system.It has been found by many researchers that there is an inverse association between the mortality from age-related diseases and the consumption of plant products [3], which could be due to the presence of various antioxidant compounds, especially, phenolics, which are the most reactive compounds. Antioxidants present in plant products help in the stimulation of cellular defence system and biological system against oxidative damage. Parkinsonia aculeata (P. aculeata) is small spiny deciduous tree, native to tropical America, and, now, it has been introduced and well cultivated in South Africa, Israel, Uganda, and India [4, 5].
It is traditionally described to treat fever and malaria and as an abortifacient [6]. The leaves of this plant are prescribed to treat rheumatism [7]. However, information pertaining to the antioxidant properties of P. aculeata is meager. However, in this study, the antioxidant activity of this plant was investigated in detail AV-951 by employing many different in vitro antioxidant assays.2. Materials and Methods2.1. Plant Material and Extraction ProcedureThe leaves of P.