or later. Patients were classified into 2 groups: group I = urgent DBE (n = 74), group II = non-urgent DBE (n = 46). Results: Baseline characteristics of patients were similar between two groups. The diagnostic yield in urgent DBE was significantly higher than non-urgent DBE (73% vs. 30%; p < 0.001). Endoscopic interventions were performed in 43% of patients in urgent DBE group whereas 13% of patients in non-urgent DBE group underwent interventions (p = 0.001). The endoscopic findings and interventions
are shown in Table 1. At 30-day after DBE, recurrent bleeding rates were not different in both groups (13% in urgent DBE vs. Proteasome inhibitor 11% in non-urgent DBE). Conclusion: Urgent DBE in overt OGIB provided significant R788 research buy higher diagnostic and therapeutic yield than non-urgent DBE. However, it did not impact on the recurrent bleeding rate. Key Word(s): 1. small bowel bleeding; 2. balloon endoscopy; 3. urgent endoscopy; Table 1 The baseline characteristics of patients and the results of DBE between two groups Baseline characteristics Urgent DBE Non-urgent DBE p-value (n = 74) (n = 46) NS: non-significant Presenting Author: THANTHAN AYE Additional Authors: AYE AYE THAN, MIN ZAW HTUN, KHIN SAN AYE Corresponding Author: THANTHAN AYE Affiliations: University of Medicine (2), Yangon Objective: Gastrointestinal stromal tumor (GISTS) is the commonest gastrointestinal mesenchymal tumor. The small intestinal GISTS
account for 30–40%. Gastrointestinal(GI) bleeding is produced by pressure necrosis and ulceration of the overlying mucosa with resultant hemorrhage from disrupted vessels, commonly present with obscure GI bleeding. Massive lower gastrointestinal bleeding is a rare and unusual symptom of GISTs, especially in young patients. GISTs mimic with tuberculosis but association is rare. Methods: A 35-year-old apparently healthy man complaining of massive bleeding per rectum had been referred to us for endoscopic evaluation. Both Upper and lower GI endoscopy did not reveal active bleeding source except blood
coming from terminal ileum. Since no cause for the GI bleed was found and due to ongoing bleeding per rectum, patient was subjected to laparotomy. A tumor about 1.5 x 2 cm at the anterior border of small intestine near jejuno-ileal junction Urocanase was found. Multiple seedlings were also noted in serosa of small intestine and peritoneum with moderate ascites. Resection of the tumor bearing portion of small bowel was done. Histology showed tumor was composed of sheets of interlacing bundles of neoplastic spindled and stroma cells. Mitosis was infrequent (<5/50HPF). The adjacent bowel wall contained scattered caseating epitheloid granulomas replete with multinucleated Langhan’s giant cells. CD 117 was positive. Histology of parietal peritoneum revealed caseating epitheloid tubercles. Chest radiography did not show pulmonary tuberculosis. Patient was treated with anti-tuberculous treatment.