However, while GO annotation of many genes that showed decreased expression correlated with the observed phenotypes, genes with increased expression (that could be potentially de-repressed) failed to show an obvious correlation. It is interesting to note that among the set o
Disclosure of potential conflict of interest: www.selleckchem.com/products/pacritinib-sb1518.html Authors declare no conflict of interest. Replication cohorts: ARIC: The Atherosclerosis Risk in Communities Study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts (HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, and HHSN268201100012C), R01HL087641, R01HL59367 and R01HL086694; National Human Genome Research Institute contract U01HG004402; and National Institutes of Health contract HHSN268200625226C.
Infrastructure was partly supported by Grant Number UL1RR025005, a component of the National Institutes of Health and NIH Roadmap for Medical Research. Work for this manuscript was supported, in part, by the Intramural Research Program of the National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS, Z01ES043012). FHS: National Heart, Lung and Blood Institute��s Framingham Heart Study (Contract No. N01-HC-25195) and its contract with Affymetrix, Inc for genotyping services (Contract No. N02-HL-6-4278). Dr. Wilk by a Young Clinical Scientist Award from the Flight Attendant Medical Research Institute (FAMRI).
A portion of this research utilized the Linux Cluster for Genetic Analysis (LinGA-II) funded by the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center. B58C: British 1958 Birth Cohort was funded by the Medical Research Council grant G0000934 and the Wellcome Trust grant 068545/Z/02 (http://www.b58cgene.sgul.ac.uk/). Genotyping was funded by the Wellcome Trust grant 076113/B/04/Z, by the United States National Institutes of Health and the Juvenile Diabetes Research Foundation U01 DK062418 and by the European Commission Framework Programme 6 (018996). Dutch Asthma Study: The Dutch Asthma study has been funded by the Netherlands Asthma Foundation grants AF 3.2.07.015; and AF 98.48 and a grant from the University Medical Center Groningen This article has in support of the manuscript online repository materials.
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