Harris Interactive Tofacitinib Citrate chemical structure Survey, 2001 had indicated that awareness changes attitudes toward CTs, enrollment, and the benefits of participation.[14] If participant is aware of the manner of conduct of a CT he/she would participate with an informed decision, recruitment will be easy and retention rate will be high. When participants are aware, compliance will increase giving better trial results. This would help the investigator for smooth conduct of a CT. Although there is an extensive literature[15?C17] evaluating the factors promoting and precluding participation in CTs among various populations, there are a limited number of studies that focus on understanding the awareness, perceptions and attitudes to participate in CTs. The aim of this study is to explore the awareness, perception and attitude towards participating in CTs among the general public in Pune.

There is an urgent need to find the public level of awareness about CTs, which will help in planning and conducting, targeted population specific education programs. MATERIALS AND METHODS Convenience sampling was used to recruit participants. None of the participants refused to participate. Participants who were friends or relatives of patients at outpatient department at a tertiary Hospital in Pune were approached face to face or by telephone. Participants were asked about their age, level of education and occupation in addition to questions about CT such as what was the source of information about CT, what did they know about CT, were they aware that participant’s consent is taken before participation and what is consent and when to give consent and if they are willing to participate.

Trial Participants were asked how was the participant’s experience with the CT, why did they participate, would he/she participate again in CT etc. Graduate and above level of education was treated as higher level of education. The interviews and FGD’s were conducted at Department of Research office during Nov and Dec 2011 by contacting people of various age group and socio economic status from Erandawane area in Pune. The interviews were conducted with Trial participants (TPs) and FGD’s and interviews were conducted with Non Trial Participants (NTPs). Individual interviews One-on-one interviews were conducted where discussion between one interviewer and one TP took place.

Focus group discussions (FGD) Were conducted with small group gatherings (8-10 people AV-951 per session) where the materials and messages were discussed in a group setting. The authors approached individuals and briefly informed them about the study, which was to assess individual’s knowledge, attitudes not and behaviour regarding CTs. All interviews were conducted in English and Marathi language. The interviewers were authors, who had no prior relationship with the individuals participated in this study.