Follow up included evaluation of bladder deformity and compliance. Results: The Small molecule library high throughput mean observation period was 8.6 years. In the 11 patients with external SI, bladder deformity and compliance significantly improved as a result of intermittent catheterization. However, of 12 patients with overactive sphincter and/or

closure pressure of 50 cm H2O or more, eight showed deterioration or no improvement in bladder deformity, and three showed upper urinary tract deterioration. Conclusion: These results indicate that an increase in urethral resistance may lead to deterioration of bladder shape. “
“Objectives: To evaluate the association of the risk and severity of lower urinary tract symptoms (LUTS) and depression diagnosed by neuropsychiatrists according selleckchem to the DSM-IV diagnostic criteria using an objective questionnaire within community-dwelling

elderly Korean men. Methods: A total of 392 men who completed urological and psychiatric evaluations as a participant in the Korean Longitudinal Study on Health and Aging were included in this analysis. From each subject, an interview elicited demographic characteristics and medical history, International Prostate Symptom Score was ascertained, and a psychiatric questionnaire was completed. Subjects were analyzed with regard to depression and LUTS severity. Results: The mean age of the subjects was 75 years, 22% were current smokers and 45% were heavy

drinkers. Two hundred and twenty-nine subjects (59%) had moderate to severe LUTS and 6.4% of the subjects were diagnosed with major depressive disorders. Those with depression showed higher International Prostate Symptom Score and lower quality of life than the euthymic group (P = 0.03 and P = 0.02, respectively). Severe LUTS was more prevalent in the depression group compared with the euthymic group (P = 0.01). Moderate to severe LUTS was associated with higher age, lower prevalence of hypertension, and higher prevalence of depression than PTK6 mild LUTS. Univariate and multivariate analyses identified age, hypertension, and depression as significant prognostic factors for moderate to severe LUTS. Depression was the most significant prognostic factor. Depression was associated with 5.81-fold increased odds of having moderate to severe LUTS. Conclusion: In older Korean men, depressive symptoms are associated with moderate to severe LUTS. “
“Objectives: To investigate the association between alcohol consumption and urinary incontinence among Japanese men. Methods: Seven hundred men aged 40–75 years were recruited from the community in middle and southern Japan.