For females, the improvement in initial period of undisturbed sleep was 2.53hr for desmopressin ODT 25100 mu g, compared with 1.32.6hr for males. No gender difference in efficacy was seen in the tablet studies. Conclusions The decrease in nocturnal voids and improvement in sleep with short-term desmopressin treatment were maintained throughout long-term treatment. A durable gender difference in efficacy in favor of females was observed with desmopressin ODT 25 mu g. Further, large-scale long-term trials are needed to confirm the durability of efficacy with gender-specific doses of desmopressin. Neurourol. Urodynam. 32: 363370, 2013. (c) 2012 Wiley Periodicals, Inc.”
“Kiwi
seed oil has a nutritionally interesting fatty acid profile, but a rather low oxidative stability, which requires Selleck SIS 3 careful extraction procedures and adequate packaging and storage. For these reasons and with the aim to achieve process intensification with shorter extraction
Z-DEVD-FMK time, lower energy consumption and higher yields, four different non-conventional techniques were experimented. Kiwi seeds were extracted in hexane using classic Soxhlet as well as under power ultrasound (US), microwaves (MWs; closed vessel) and MW-integrated Soxhlet. Supercritical CO2 was also employed and compared to the other techniques in term of yield, extraction time, fatty acid profiles and organoleptic properties. All these non-conventional techniques are fast, effective and safe. A sensory evaluation test showed the presence of off-flavours in oil samples extracted by Soxhlet and US, an indicator of partial degradation.”
“Aim To evaluate the prevalence and risk factors of urinary incontinence (UI) and its effects on quality of life in women aged between 35
and 64 years. Methods Data were obtained from the 2005 National Health Interview survey, in which 4,661 women aged between 35 and 64 years responded to questions concerning UI occurrence and health-related quality AZD1208 JAK/STAT inhibitor of life (HRQL), assessed using the Short Form 36, Taiwan version. Chi-square tests and multiple logistic regressions were applied to analyze comorbidity and risk factors of UI. Multivariable liner regression was used to evaluate the association between UI and HRQL. Results The weighted UI prevalence in Taiwanese women aged 3544, 4554 years, and 5564 years were 14.7%, 24.7%, and 32.4%, respectively. After adjustment, increased age, greater parity, higher BMI (body mass index), former HRT use, having a psychiatric disease, hyperlipidemia, and respiratory disease were identified as significant UI risk factors. Women with UI had significantly lower scores on all SF-36 dimensions. After adjusting for other factors, UI remained a significant predictor of all domains of SF-36 and was associated with reduced physical (by 2.31 points) and mental (by 2.76 points) component summary scores. From a mental health perspective, UI had a greater influence on HRQL than diabetes, hyperlipidemia, and chronic kidney disease.